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Two hundred fifty bacterias isolated in significant numbers from 217 specimens of urine and 79 organisms from 79 acute urethral discharge between Jan. 1973 and Dec. 1973. were evaluated and the following results were obtained. 1. Of a total of 250 bacterial strains isolated by cultures of the urine. 87.2% was gram-negative bacteria and 12.8% was gram-positive. Isolated organisms include E. coli (33.6%), Klebsiella(14.8%), Colifom bacilli (11.2%), .Alcaligenes (10%), Streptococcus (7.6%), Pseudomonas (6%) and Proteus (5.2%) in order of frequency. 2. There was a striking difference between the bacterial flora in the urine of patients with acute urinary tract infection and that in the urine of patients with chronic urinary tract infection. Acute urinary tract infection was mainly caused by a strain of E. coli (53.1%). In chronic urinary tract infection, the relative incidence of infection caused by more antimicrobial-resistant gram-negative barcilli such as Klebsiella, Pseudomonas, Proteus, and Alcaligenes and that of infection caused by E. coli was 21.25. Sum of Klebsiella, Pseudomonas, Proteus, and Alcaligenes in acute urinary tract infection was 14.1% and in chronic urinary tract infection was 45. 5%. 3. Above the 85% of Klebsiella, Pseudomonas, and Alcaligenes was resistant to six kinds of antibiotics, which were Penicillin G., Streptomycin. Chloramphtnicol, Tetracycline, Kanamycin and AmpiciIlin, 67.2% of 8. coli and 54.8% of Proteus were resistant to that.
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